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January 30, 2013

Previously Unknown Mechanism of Memory Formation

It takes a lot to make a memory.

New proteins have to be synthesized, neuron structures altered.

While some of these memory-building mechanisms are known, many are not.

Some recent studies have indicated that a unique group of molecules called microRNAs, known to control production of proteins in cells, may play a far more important role in memory formation than previously thought.

Now, a new study by scientists on the Florida campus of The Scripps Research Institute has for the first time confirmed a critical role for microRNAs in the development of memory in the part of the brain called the amygdala, which is involved in emotional memory. The new study found that a specific microRNA—miR-182—was deeply involved in memory formation within this brain structure.

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